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CBSE
Class 12
Biology
Biology
Principles of Inheritance and Variation

Question Bank

Practice Hub

Question Bank: Principles of Inheritance and Variation

This chapter explores the principles of inheritance and variation, focusing on how traits are passed from parents to offspring and the genetic mechanisms behind this process.

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Start with curated question sets, move into full module views when needed, and keep discovering related practice without losing your place in the chapter.

Question Bank - Principles of Inheritance and Variation

View all (89)
Q1.

What is the term used for the physical expression of genetic traits?

Single Answer MCQ
Q-00084109
View explanation
Q2.

According to Mendel's Law of Segregation, how are alleles distributed to gametes?

Single Answer MCQ
Q-00084110
View explanation
Q3.

In Mendel's experiments, what ratio did he observe in the F2 generation for a monohybrid cross?

Single Answer MCQ
Q-00084111
View explanation
Q4.

What was the main focus of Mendel's studies on pea plants?

Single Answer MCQ
Q-00084112
View explanation
Q5.

Which type of cross did Mendel perform to observe segregation of traits?

Single Answer MCQ
Q-00084113
View explanation
Q6.

What does it mean if an organism is homozygous for a trait?

Single Answer MCQ
Q-00084114
View explanation
Q7.

What phenomenon explains why two traits appear together in offspring?

Single Answer MCQ
Q-00084115
View explanation
Q8.

What did Mendel discover about the inheritance of traits?

Single Answer MCQ
Q-00084116
View explanation
Q9.

If a pea plant has genotype Tt for tallness, what does 'T' represent?

Single Answer MCQ
Q-00084117
View explanation
Q10.

How did Mendel ensure that he was working with true-breeding plants?

Single Answer MCQ
Q-00084118
View explanation
Q11.

Which concept of inheritance states that the effect of one allele can mask the effect of another?

Single Answer MCQ
Q-00084119
View explanation
Q12.

What ratio do phenotypes typically display in a dihybrid cross of two heterozygotes?

Single Answer MCQ
Q-00084120
View explanation
Q13.

Why are linked genes less likely to assort independently during inheritance?

Single Answer MCQ
Q-00084121
View explanation
Q14.

In terms of inheritance, what is a key characteristic of co-dominance?

Single Answer MCQ
Q-00084122
View explanation
Q15.

How did Mendel's work contribute to the field of genetics?

Single Answer MCQ
Q-00084123
View explanation
Q16.

What is the ratio of phenotypes in the F2 generation from a dihybrid cross between two heterozygous parents?

Single Answer MCQ
Q-00084124
View explanation
Q17.

In Mendelian genetics, what does dominance refer to?

Single Answer MCQ
Q-00084125
View explanation
Q18.

Which of the following correctly describes the genotype of a plant with yellow seeds (Y) and round seeds (R)?

Single Answer MCQ
Q-00084126
View explanation
Q19.

What is the primary mechanism of sex determination in humans?

Single Answer MCQ
Q-00084127
View explanation
Q20.

What is the expected percentage of F2 generation with green seeds if yellow is dominant in a dihybrid cross?

Single Answer MCQ
Q-00084128
View explanation
Q21.

In the XO type of sex determination, what is the genetic makeup of males?

Single Answer MCQ
Q-00084129
View explanation
Q22.

Which of the following represents an example of incomplete dominance?

Single Answer MCQ
Q-00084130
View explanation
Q23.

How does the presence of the Y chromosome affect the sex of human offspring?

Single Answer MCQ
Q-00084131
View explanation
Q24.

In a dihybrid cross involving a gene for seed shape (R and r) and seed color (Y and y), what will be the expected genotype ratio in the F2 generation?

Single Answer MCQ
Q-00084132
View explanation
Q25.

What type of gametes do males produce in the XY sex determination system?

Single Answer MCQ
Q-00084133
View explanation
Q26.

If a plant with the genotype YyRr is crossed with a plant of genotype yyrr, what proportion of the offspring will have yellow, round seeds?

Single Answer MCQ
Q-00084134
View explanation
Q27.

In birds, which sex chromosomes are responsible for determining the female offspring?

Single Answer MCQ
Q-00084135
View explanation
Q28.

What does the term 'dihybrid cross' refer to?

Single Answer MCQ
Q-00084136
View explanation
Q29.

What is the defining characteristic of haplodiploidy in honey bees?

Single Answer MCQ
Q-00084137
View explanation
Q30.

In pea plants, which trait for seed color is dominant?

Single Answer MCQ
Q-00084138
View explanation
Q31.

What type of chromosomal arrangement governs the sex of offspring in parthenogenetic species?

Single Answer MCQ
Q-00084139
View explanation
Q32.

In Mendelian inheritance, the phenotypic ratio of 9:3:3:1 arises from which type of genetic cross?

Single Answer MCQ
Q-00084140
View explanation
Q33.

Which of the following statements accurately describes the gamete production in males of xy type organisms?

Single Answer MCQ
Q-00084141
View explanation
Q34.

When crossing two dihybrids for traits with complete dominance, what is the expected ratio of dominant to recessive traits?

Single Answer MCQ
Q-00084142
View explanation
Q35.

What is the sex of an offspring if an ovum is fertilized by a sperm containing an X chromosome?

Single Answer MCQ
Q-00084143
View explanation
Q36.

For which of the following traits in pea plants did Mendel observe that round shape is dominant over wrinkled?

Single Answer MCQ
Q-00084144
View explanation
Q37.

Which of the following organisms exhibit male heterogamety?

Single Answer MCQ
Q-00084145
View explanation
Q38.

If a plant that is heterozygous for seed color (Yy) is crossed with a homozygous recessive plant (yy), what percentage of offspring will be yellow?

Single Answer MCQ
Q-00084146
View explanation
Q39.

The 'W' chromosome in birds is indicative of which sex?

Single Answer MCQ
Q-00084147
View explanation
Q40.

What type of genetic variance allows traits to be expressed in multiple ways?

Single Answer MCQ
Q-00084148
View explanation
Q41.

Which statement about the male sex-determining mechanism in some insects is incorrect?

Single Answer MCQ
Q-00084149
View explanation
Q42.

In plants, if the genotype of a round and yellow seed is RrYy, what gametes can it produce?

Single Answer MCQ
Q-00084150
View explanation
Q43.

What is the purpose of the sex chromosomes in organisms?

Single Answer MCQ
Q-00084151
View explanation
Q44.

Which of the following statements best describes female birds in terms of chromosome composition?

Single Answer MCQ
Q-00084152
View explanation
Q45.

What is a point mutation?

Single Answer MCQ
Q-00084153
View explanation
Q46.

Which of the following disorders is an example of a mutation?

Single Answer MCQ
Q-00084154
View explanation
Q47.

What is the effect of frameshift mutations?

Single Answer MCQ
Q-00084155
View explanation
Q48.

What are mutagens?

Single Answer MCQ
Q-00084156
View explanation
Q49.

Which mutation leads to the greatest change in a genetic sequence?

Single Answer MCQ
Q-00084157
View explanation
Q50.

How can mutations lead to cancer?

Single Answer MCQ
Q-00084158
View explanation
Q51.

Which of the following is not a consequence of mutation?

Single Answer MCQ
Q-00084159
View explanation
Q52.

What is the main difference between aneuploidy and polyploidy?

Single Answer MCQ
Q-00084160
View explanation
Q53.

Which type of mutation can arise from exposure to UV radiation?

Single Answer MCQ
Q-00084161
View explanation
Q54.

Which of the following best explains the term 'silent mutation'?

Single Answer MCQ
Q-00084162
View explanation
Q55.

Which genetic disorder is an example of a chromosomal mutation?

Single Answer MCQ
Q-00084163
View explanation
Q56.

What role do repair enzymes play in mutation?

Single Answer MCQ
Q-00084164
View explanation
Q57.

Which condition results from a deletion mutation?

Single Answer MCQ
Q-00084165
View explanation
Q58.

What is a common method used to induce mutations in laboratory settings?

Single Answer MCQ
Q-00084166
View explanation
Q59.

What is the purpose of studying mutations in genetics?

Single Answer MCQ
Q-00084167
View explanation
Q60.

What is the term used for the observable characteristics of an organism?

Single Answer MCQ
Q-00084168
View explanation
Q61.

In Mendelian genetics, what is the genotype of a true-breeding dwarf pea plant?

Single Answer MCQ
Q-00084169
View explanation
Q62.

What was the phenotypic ratio observed in Mendel's F2 generation for a monohybrid cross?

Single Answer MCQ
Q-00084170
View explanation
Q63.

If a pea plant has the genotype Tt, which of the following describes its phenotype?

Single Answer MCQ
Q-00084171
View explanation
Q64.

What term describes different forms of a gene, such as those for tall and dwarf traits?

Single Answer MCQ
Q-00084172
View explanation
Q65.

In Mendel's experiments, what did he call the units of inheritance?

Single Answer MCQ
Q-00084173
View explanation
Q66.

What does the 'dominant' allele do in a heterozygous genotype?

Single Answer MCQ
Q-00084174
View explanation
Q67.

How many phenotypes will appear in the F1 generation when crossing a true-breeding tall plant with a true-breeding dwarf plant?

Single Answer MCQ
Q-00084175
View explanation
Q68.

What concept explains that in a heterozygote, one allele often masks the other?

Single Answer MCQ
Q-00084176
View explanation
Q69.

What is the probability of getting a dwarf plant from a self-pollination of a heterozygous tall plant (Tt)?

Single Answer MCQ
Q-00084177
View explanation
Q70.

What type of cross would you use to determine the genotype of an unknown plant?

Single Answer MCQ
Q-00084178
View explanation
Q71.

Mendel's experiments demonstrated which of the following principles?

Single Answer MCQ
Q-00084179
View explanation
Q72.

In a monohybrid cross, what is the expected genotype ratio in the F2 generation?

Single Answer MCQ
Q-00084180
View explanation
Q73.

Which principle is illustrated by the observation that a dominant trait can mask a recessive trait?

Single Answer MCQ
Q-00084181
View explanation
Q74.

If a plant with genotype 'Tt' self-fertilizes, what phenotypic ratio will appear in their offspring?

Single Answer MCQ
Q-00084182
View explanation
Q75.

In a genetic cross involving a dominant and a recessive trait, how can you visually represent the possible offspring outcomes?

Single Answer MCQ
Q-00084183
View explanation
Q76.

What type of mutation is responsible for sickle cell anemia?

Single Answer MCQ
Q-00084184
View explanation
Q77.

Which disorder is characterized by an additional copy of chromosome 21?

Single Answer MCQ
Q-00084185
View explanation
Q78.

What is the genetic basis of hemophilia?

Single Answer MCQ
Q-00084186
View explanation
Q79.

Which of the following is a feature of Turner’s syndrome?

Single Answer MCQ
Q-00084187
View explanation
Q80.

What is the inheritance pattern for color blindness?

Single Answer MCQ
Q-00084188
View explanation
Q81.

Which of these genetic disorders is associated with the presence of an extra X chromosome in males?

Single Answer MCQ
Q-00084189
View explanation
Q82.

What is a common symptom of cystic fibrosis?

Single Answer MCQ
Q-00084190
View explanation
Q83.

In pedigree charts, what symbol represents a female?

Single Answer MCQ
Q-00084191
View explanation
Q84.

Why are males more frequently affected by X-linked disorders?

Single Answer MCQ
Q-00084192
View explanation
Q85.

What type of genetic disorder is phenylketonuria (PKU)?

Single Answer MCQ
Q-00084193
View explanation
Q86.

What is the mode of inheritance for Tay-Sachs disease?

Single Answer MCQ
Q-00084194
View explanation
Q87.

What is a common characteristic of autosomal dominant disorders?

Single Answer MCQ
Q-00084195
View explanation
Q88.

What is the primary cause of Klinefelter's syndrome?

Single Answer MCQ
Q-00084196
View explanation
Q89.

Which genetic disorder can result from mutations in the CFTR gene?

Single Answer MCQ
Q-00084197
View explanation
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